Nampt-IN-1

Product Name: Nampt-IN-1
CAS No.: 1698878-14-6
Chemical Name: Nampt-IN-1
Synonyms: LSN3154567;Nampt-IN-1;Nampt inhibitor 1;LSN3154567 (Nampt-IN-1);LSN 3154567;LSN-3154567;LSN3154567;2-hydroxy-2-methyl-N-[1,2,3,4-tetrahydro-2-[2-(3-pyridinyloxy)acetyl]-6-;2-Hydroxy-2-methyl-N-[1,2,3,4-tetrahydro-2-[2-(3-pyridinyloxy)acetyl]-6-isoquinolinyl]-1-propanesulfonamide;2-hydroxy-2-methyl-N-(2-(2-(pyridin-3-yloxy)acetyl)-1,2,3,4-tetrahydroisoquinolin-6-yl)propane-1-sulfonamide;1-Propanesulfonamide, 2-hydroxy-2-methyl-N-[1,2,3,4-tetrahydro-2-[2-(3-pyridinyloxy)acetyl]-6-isoquinolinyl]-;LSN-3154567,NAMPT,PBEF,Nampt IN 1,Visfatin,inhibit,Pre-B cell colony enhancing factor,Nicotinamide phosphoribosyl transferase,Inhibitor,NamptIN1,LSN 3154567
CBNumber: CB53048664
Molecular Formula: C20H25N3O5S
Formula Weight: 419.49
MOL File: 1698878-14-6.mol

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Nampt-IN-1 Property

Boiling point:: 659.9±65.0 °C(Predicted)
Density: 1.363±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: Soluble
form: powder
pka: 8.67±0.20(Predicted)
color: white to beige

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML2249
Product name: LSN3154567
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $107
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML2249
Product name: LSN3154567
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $430
Updated: 2024/03/01

Cayman Chemical

Product number: 26066
Product name: Nampt-IN-1
Purity: ≥98%
Packaging: 1mg
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 26066
Product name: Nampt-IN-1
Purity: ≥98%
Packaging: 5mg
Price: $172
Updated: 2024/03/01

Cayman Chemical

Product number: 26066
Product name: Nampt-IN-1
Purity: ≥98%
Packaging: 10mg
Price: $321
Updated: 2024/03/01

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Nampt-IN-1 Chemical Properties,Usage,Production

Description

Nampt-IN-1 is a potent inhibitor of nicotinamide phosphoribosyltransferase (Nampt; IC₅₀ = 3.1 nM). It is selective for Nampt over a panel of greater than 100 human kinases at 1 μM. Nampt-IN-1 inhibits NAD⁺ formation in and proliferation of HCT116 cells (IC₅₀s = 1.8 and 8.9 nM, respectively). It inhibits cell growth in a panel of cancer cell lines (IC₅₀s = <0.2-2 μM). Nampt-IN-1 inhibits NAD⁺ formation in an A2780 ovarian carcinoma mouse xenograft model (ED₅₀ = 2 mg/kg).

Uses

Nampt-IN-1 functions as a co-drug. Nampt-IN-1 is a potent and selective NAMPT inhibitor.

Biochem/physiol Actions

LSN3154567 might be useful in developing a novel cancer therapeutic.

Nampt-IN-1 Preparation Products And Raw materials

Raw materials

Preparation Products

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Nampt-IN-1 Suppliers

China 47 United States 8 Global 55

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4662
Advantage: 60

Aladdin Scientific

Tel: +1-833-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 52927
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354
Email: support@targetmol.com
Country: United States
ProdList: 19973
Advantage: 58

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9926
Advantage: 65

1698878-14-6, Nampt-IN-1Related Search:

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2-hydroxy-2-methyl-N-(2-(2-(pyridin-3-yloxy)acetyl)-1,2,3,4-tetrahydroisoquinolin-6-yl)propane-1-sulfonamide

2-Hydroxy-2-methyl-N-[1,2,3,4-tetrahydro-2-[2-(3-pyridinyloxy)acetyl]-6-isoquinolinyl]-1-propanesulfonamide

LSN3154567 (Nampt-IN-1)

LSN3154567

2-hydroxy-2-methyl-N-[1,2,3,4-tetrahydro-2-[2-(3-pyridinyloxy)acetyl]-6-

LSN 3154567;LSN-3154567;LSN3154567

Nampt inhibitor 1

1-Propanesulfonamide, 2-hydroxy-2-methyl-N-[1,2,3,4-tetrahydro-2-[2-(3-pyridinyloxy)acetyl]-6-isoquinolinyl]-

LSN-3154567,NAMPT,PBEF,Nampt IN 1,Visfatin,inhibit,Pre-B cell colony enhancing factor,Nicotinamide phosphoribosyl transferase,Inhibitor,NamptIN1,LSN 3154567

1698878-14-6